Homer proteins and metabotropic glutamate receptor interaction on sleep in Drosophila melanogaster

Takeaway

  • Homer proteins and metabotropic glutamate receptors (mGluRs) interact in Drosophila melanogaster and are necessary in the sleep regulation process.

Why this matters

  • Synaptic plasticity during sleep is an important regulatory process that is poorly understood.

  • Homer proteins and mGluRs interact and are involved in plasticity; however, their role in behavioral and sleep regulation is unknown.