Hypoxemia in obstructive sleep apnea affects functional connectivity in the default mode network

Takeaway

  • Functional connectivity in the default mode network (DMN) correlates with apnea-hypopnea index (AHI), oxygen desaturation index (ODI) and nadir SaO2, but not sleep fragmentation, in people with obstructive sleep apnea (OSA).

Why this matters

  • Decreased functional connectivity in the DMN has been reported in people with OSA.

  • A better understanding of how hypoxemia affects functional connectivity and cognition in people with OSA, may guide future treatment strategies.