Ictal downbeat nystagmus in individuals with Meniere’s disease


  • Downbeat nystagmus could be observed during attacks of unilateral Meniere’s disease (MD) due to an asymmetry in the vertical vestibulo-ocular reflex (VOR) or saccular dysfunction.

Why this matters ?

  • Lesions in the vestibulocerebellum may attribute to pure or predominant downbeat nystagmus in individuals. The exact mechanism of downbeat nystagmus is not currently known.

  • In a previous report, relative hypofunction of the posterior semicircular canals (PCs) was suggested to cause ictal downbeat nystagmus among individuals with MD.

  • The results of this study suggest that individuals with recurrent audio vestibulopathy and ictal downbeat nystagmus should be considered for an MD diagnosis.