Imaging-guided laser procedure may reduce gelastic seizures in patients with hypothalamic hamartoma


  • Magnetic resonance imaging (MRI)-guided laser interstitial thermal therapy (LITT) is a minimally invasive neurosurgical procedure offering superior seizure control and similar adverse effects as more traditional surgical procedures for hypothalamic hamartomas.

Why this matters

  • Limited information exists about long-term outcomes after MRI-LITT for hypothalamic hamartomas, a rare developmental nonneoplastic lesion associated with gelastic seizures refractory to medical therapy.