Imaging marker to stratify recurrent intracerebral hemorrhage in cerebral amyloid angiopathy


  • Convexity subarachnoid hemorrhage (cSAH) can be detected by non-contrast computed tomography (CT) in a proportion of patients with acute lobar intracerebral hemorrhage (ICH) related to cerebral amyloid angiopathy (CAA); cSAH appears to be an important prognostic marker of increased risk of recurrent ICH, independent from cortical superficial siderosis (cSS).

Why this matters ?

  • cSS has proven to be a useful imaging biomarker to predict high risk of recurrent ICH but is visible only on magnetic resonance imaging (MRI); identifying a new prognostic marker for assessment in the acute setting with non-contrast CT would increase access to diagnostic approaches.