Imaging reveals pattern of atrophy distinct to hippocampal sclerosis of aging

Takeaway

  • Magnetic resonance imaging (MRI) revealed a distinct pattern of atrophy to cornu ammonis 1 (CA1) and the subiculum in people with hippocampal sclerosis of aging (HS) compared with both people with and people without Alzheimer’s disease (AD) neuropathology.

Why this matters

    Imaging of CA1 and subiculum atrophy has potential as an in vivo biomarker for HS.