Improving voxel-wise genome-wide association analysis for imaging biomarkers in Alzheimer’s disease

Takeaway

  • A nonlocal method that incorporates spatial correlations was developed to improve the speed and efficiency of voxel-wise genome-wide association analysis (vGWAS) for the detection of biomarkers in Alzheimer’s disease (AD).

Why this matters

    Detection of biomarkers of (AD) is crucial for disease diagnosis and monitoring, but the approach of vGWAS, while holistic, is also time-consuming and computationally intensive.