In utero exposure to dichloroacetic acid impairs cognitive function in the adulthood

Takeaway

  • Fetal exposure to dichloroacetic acid can impair the synaptic plasticity and cognition function of rats in adulthood.

Why this matters

    Dichloroacetic acid is a by-product of disinfection in drinking water and is a recognized carcinogen in both humans and animals. These novel findings further our understanding of the molecular mechanisms underlying the neurotoxicity of dichloroacetic acid and provide a strong argument for avoiding exposure to this chemical during pregnancy.