Incidence estimates for de novo monogenic neurodevelopmental disorders

Takeaway

  • A catalogue of incidence estimates for disorders caused by de novo variants (DNVs) can help inform strategic decision-making where epidemiological data are not available.

Why this matters

    Although de novo mutations have a significant role in the development of rare neurodevelopmental disorders, epidemiological estimates are lacking. These findings may help clinicians and researchers guide health policy planning.