Indication of cognitive impairment by white matter abnormality after minor stroke in older patients


  • Magnetic resonance imaging (MRI)-detected white matter hyperintensity (WMH) may be less valuable for assessing cognitive impairment (CI) following transient ischemic attack (TIA) or nondisabling stroke (NDS) in older patients.

Why this matters

  • MRI-detected WMH is associated with CI following TIA/NDS, but white matter (WM) abnormalities are also observed in older individuals without CI.

  • Determining the relevance of MRI-detected WMH as an indicator of CI after TIA/NDS in older individuals may impact clinical use of this assessment approach.