Induced seizures are as effective as spontaneous seizures in identifying the epileptogenic zone


  • Seizures induced by cortical stimulation are as effective as spontaneously induced seizures in identifying the epileptogenic zone.

Why this matters

  • In patients with epilepsy, cortical stimulation is used in association with intracranial electroencephalography (EEG) to define the epileptic generator zone and for functional mapping.

  • There have been very few studies evaluating the association between cortical stimulation and surgical outcomes.

  • Identifying the epileptogenic zone and therefore the seizure-onset zone (SOZ) through cortical stimulation may shorten the length of time needed for presurgical evaluation and is associated with positive postsurgical outcomes.