Interictal dysphoric disorder is not an epilepsy-specific illness


  • Interictal dysphoric disorder is not specific for epilepsy but occurs with comparable prevalence and severity in people with depression with and without epilepsy.

Why this matters

  • Depression often accompanies epilepsy. Historically, interictal dysphoric disorder was regarded as an affective disorder that only occurred in people with epilepsy, but the epilepsy-specific nature of this disorder has recently been refuted.

  • These findings support topical reports that interictal dysphoric disorder should not be viewed as an epilepsy-specific condition.