Interictal epileptiform discharges (IEDs) in the hippocampus have been observed to modulate neurons that are involved in memory formation and recall.
Why this matters
It is not well understood why patients with memory deficits are often seen with IEDs on interictal electroencephalography.
These IEDs have been previously associated with transient cognitive impairments.
Developing the understanding of how IEDs affect individual neurons is important for developing our knowledge of memory impairments in epilepsy patients.