Interindividual variability that promotes vulnerability to sleep loss-related neurobehavioral effects


  • Identifying factors in those most susceptible to the negative impacts of sleep loss will provide substantial clinical benefit.

Why this matters

  • The benefits of sleep are well established; however, 15% of US adults report sleeping less than 7 hours a night. Sleep loss results in a range of adverse effects, such as impacts on neurobehavior, particularly vigilant attention.

  • Vigilant attention deficit from sleep loss varies substantially between individuals, from marked, moderate, or mild to no decrements. Findings of neurobehavioral responses to sleep loss between individuals remain inconsistent and unexplained despite being well-documented.