Iron metabolic parameters in sporadic amyotrophic lateral sclerosis

Takeaway

  • Patients with sporadic amyotrophic lateral sclerosis (sALS) had increased overall serum ferritin levels; however, females had decreased serum transferrin levels. Higher serum ferritin was associated with reduced survival.

Why this matters ?

  • Change in iron metabolism may predict disease progression and prognosis in people with sALS.