This study provides novel evidence for apathy as a prodrome of dementia.
Why this matters
The prevalence of dementia is increasing, and therefore as is the interest in identifying preclinical markers of cognitive decline. Apathy is the most common neuropsychiatric symptom among dementia subtypes and is considered to be a highly informative neuropsychiatric risk state. No existing studies, however, have investigated apathy as an independent risk factor for, or prodrome of, dementia in a diverse sample of cognitively normal older adults.