Is there a link between cognitive reserve, psychological resilience and cognitive functioning in small vessel disease?


  • Cognitive reserve has robust associations with objective and subjective cognitive functioning in people with white matter hyperintensities.

Why this matters

  • Although cerebral small vessel disease is characterized by progressive white matter hyperintensities and cognitive decline, the reasons underlying variability in cognitive capabilities remains unclear.

  • By identifying individual factors that affect cognitive functioning in small vessel disease, these important findings further our understanding of the clinical progression of the disease which could ultimately lead to improved treatments.