Patients with a history of vigorous physical activity (VPA) in adolescence and early adulthood were significantly more likely to be diagnosed with ALS before the age of 60.
Why this matters
Amyotrophic lateral sclerosis (ALS) is a complex multifactorial neurodegenerative disease that typically results in death within 2–5 years from diagnosis. Risk factors and causes of the disease are still largely unknown.
Improving understanding of VPA as an ALS risk factor may help clinicians make more rapid diagnoses and result in earlier therapeutic interventions.