Is there an association between migraine and atrial fibrillation?

Takeaway

  • Migraine with aura was significantly associated with atrial fibrillation in two large prospective population-based studies.

Why this matters

  • Patients with migraine are at increased risk of ischemic stroke, which may be due to cortical spreading depression, endothelial dysfunction, and/or genetic factors.

  • Atrial fibrillation is a treatable risk factor for stroke, and these results suggest it may be beneficial to screen patients with migraine for this heart condition.