Laser resection for mesial temporal lobe epilepsy: manual versus automated trajectory planning


  • Simulated outcomes with automated laser trajectory planning (ALTP) were better than actual outcomes with manual laser trajectory planning (MLTP) for laser interstitial thermal therapy (LITT) to treat mesial temporal lobe epilepsy (MTLE).

Why this matters

  • LITT is a minimally invasive technique for amygdalohippocampectomy (AHX) to treat MTLE; success depends on laser trajectory and ablation volume, and better complication rates are desirable.

  • Clinicians consider many parameters with MLTP for LITT (for example, avoidance of collateral structures).

  • ALTP could standardize parameter consideration, improving LITT safety and efficacy.