Late seizure recurrence following epilepsy surgery

Takeaway

  • Complete lesion resection was the most important factor driving sustained freedom from seizure relapse.

Why this matters

  • Patients with epilepsy that does not respond to antiepileptic drugs can be successfully treated with epilepsy surgery to remove epileptogenic lesions, with ~65% of patients experiencing “good outcomes”.

  • Sustained freedom from seizures is believed to decline over time. Some patients experience several seizure-free years before relapsing. There is limited data available to explain why relapse occurs in these cases.