Complete lesion resection was the most important factor driving sustained freedom from seizure relapse.
Why this matters
Patients with epilepsy that does not respond to antiepileptic drugs can be successfully treated with epilepsy surgery to remove epileptogenic lesions, with ~65% of patients experiencing “good outcomes”.
Sustained freedom from seizures is believed to decline over time. Some patients experience several seizure-free years before relapsing. There is limited data available to explain why relapse occurs in these cases.