Link between reduced tissue infarct and treatment with intravenous alteplase in acute stroke?

Takeaway

  • Administration of intravenous alteplase in treatment of acute stroke was not associated with changes in ischemic brain edema formation but was associated with reduced tissue infarct volume.

Why this matters

  • Alteplase may improve functional outcomes in acute middle cerebral artery stroke through reducing tissue infarct, but further research is required to assess interventions to mitigate ischemic brain edema.

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