Link between reduced tissue infarct and treatment with intravenous alteplase in acute stroke?


  • Administration of intravenous alteplase in treatment of acute stroke was not associated with changes in ischemic brain edema formation but was associated with reduced tissue infarct volume.

Why this matters

    Alteplase may improve functional outcomes in acute middle cerebral artery stroke through reducing tissue infarct, but further research is required to assess interventions to mitigate ischemic brain edema.

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