Long-term outcomes of patients with different clinical and radiological manifestations of ischemic stroke

Takeaway

  • Patients with silent vascular lesions, imaging negative ischemia, and symptomatic cerebrovascular disease showed different patterns of brain volume loss and recurrent cerebrovascular lesion development over 12 years.

Why this matters

  • The clinical and radiological findings of ischemic stroke do not always correlate, and it is unclear to what extent they predict disease progression and future stroke recurrence.

  • The study provides evidence that the different clinical and radiological manifestations of cerebrovascular disease should be considered separately in clinical research and practice.