Longitudinal analysis of gastrointestinal symptoms and cognitive decline in Parkinson’s disease


  • In those newly diagnosed with Parkinson’s disease (PD), gastrointestinal (GI) symptom frequency is predictive of longitudinal cognitive decline.

Why this matters

    GI symptoms, which may emerge prior to motor symptoms in PD, may contribute to cognitive decline in PD and serve as a useful marker for those at elevated risk for cognitive decline.