Lumbar nerve root lesions in a case of neuromyelitis optica spectrum disorder


  • Radiculopathy without myelopathy is unusual but can occur in individuals with anti-aquaporin-4 (AQP4) antibody positive neuromyelitis optica spectrum disorder (NMOSD).

Why this matters

    NMOSD is an autoimmune disease which affects the optic nerve and spinal cord. Recent reports have indicated that NMOSD can affect peripheral nerves. However, the pathomechanism for the involvement of the peripheral nervous system remains unclear. The results of this study will help clinicians become aware of radiculopathy as a part of the presentation of NMOSD.