Magnetic resonance imaging to distinguish benign and malignant tumours in neurofibromatosis type 1


  • Functional, diffusion-weighted magnetic resonance imaging (DW MRI) parameters provide sensitive and specific distinction between malignant and benign peripheral nerve sheath tumours (PNSTs) in patients with neurofibromatosis type 1 (NF1).

Why this matters

  • Techniques for reliable identification of malignant PNSTs are needed to support earlier surgical tumour resection and lower mortality in patients with NF1.