The presence of delta wave slowing ≥1.4 Hz on scalp electroencephalogram (EEG) was correlated with intracranial interictal epileptiform discharges (IEDs) in patients with temporal lobe epilepsy.
Why this matters
Localization of IEDs using scalp EEG can identify the epileptogenic zone. However, some IEDs, particularly those within the temporal lobe, cannot be detected with this method.
This was the first study to record both intracranial and scalp EEG simultaneously, and may contribute to the development of a scalp marker for intracranial IEDs, allowing less invasive detection in the future.