Inner-eye percentage difference (IEPD) or inter-eye absolute difference (IEAD) calculated using optical coherence tomography (OCT) can be recommended as an additional supportive test for the diagnosis of multiple sclerosis (MS) in young individuals with less than five co-morbidities.
Why this matters
MS is a debilitating disease which predominately affects young adults in the prime of their working life. There is a need for accurate diagnostic criteria so individuals with MS can access approved disease modifying treatments. A previous revision of the diagnostic criteria for MS highlighted the value of including OCT as a complementary diagnostic test. The results of this study provide the first evidence that OCT scans can contribute to the diagnosis of MS which may help reduce the need for invasive and costly procedures.