Metabolomic profiles and incident ischemic stroke

Takeaway

  • A stroke metabolite score (SMS) that includes metabolites associated with ischemic stroke has improved risk prediction than traditional risk factors.

Why this matters

  • Women account for almost 60% of stroke-related deaths. The lifetime risk of stroke in women is 20% higher than males, with metabolomic factors more strongly associated to stroke in women than men.

  • Only a few studies have explored the metabolomic profiles associated with ischemic stroke in both men and women.