Microglial dysfunction and innate immunity: insights from the transcriptome

Researchers in Hong Kong have used single-cell transcriptome profiling to identify new therapeutic targets for patients with Alzheimer’s disease (AD).

Microglial dysfunction plays a central role in the pathogenesis of AD, according to Professor Nancy Ip of the Hong Kong University of Science and Technology in Clear Water Bay, Hong Kong, presenting in a plenary session at AAIC 2021.