Microsleep evaluation in people with Parkinson’s disease

Takeaway

  • In people with Parkinson’s disease (PD), sleep microstructure is severely altered, and this dysfunction is associated with diminished noradrenaline transporter density of the noradrenergic arousal system.

Why this matters ?

    Up to 98% of PD patients report sleep-wake disturbances despite studies finding no differences between people with PD and control populations in sleep macrostructure (sleep stages, sleep efficiency, etc.); thus, a closer look at sleep microstructure in people with PD is warranted.