Microstate dynamics and large-scale network fluctuations in Lewy body dementia

Takeaway

  • Microstate dynamics in Lewy body dementia are significantly slowed compared to Alzheimer’s disease (AD) and normal aging and relate to cognitive fluctuations measured by functional magnetic resonance imaging (fMRI).

Why this matters

  • This investigation into electroencephalogram (EEG) microstate dynamics and fMRI in Lewy body dementia indicates a link between large-scale network fluctuations in the cortical-basal ganglia-thalamic loop and microstate dynamics.