Multimorbidity in motor neuron disease


  • Most people with motor neuron disease (MND) have two or more comorbidities, however age remains the greatest prognostic factor for survival.

Why this matters

  • MND is a progressive neurodegenerative disorder with a typically poor and short prognosis.

  • It is believed that many people with MND have multiple comorbid conditions that could potentially impact survival. Multimorbidity is associated with increased clinical complexity, including polypharmacy and greater disability, as well as advancing age.

  • The prevalence of multimorbidity in MND and the potential relationship with survival remains understudied.