Muscular ischemia in people with dermatomyositis with anti-nuclear matrix protein-2 antibodies

Takeaway

  • Prominent involvement of perimysial arterioles leads to muscle ischemia in people with anti- nuclear matrix protein-2 (NXP-2) antibodies dermatomyositis (DM).

Why this matters

    It has previously been proposed that the primary cause of muscular ischemia lies upstream, at the level of perimysial arteries in DM.