Neuregulin-1-beta 1 dysregulation associated with multiple sclerosis pathogenesis and progression

Takeaway

  • In people with early multiple sclerosis (MS), plasma levels of neureulin-1 beta 1 (Nrg-1β1) are reduced and associated with progression of relapsing-remitting MS (RRMS).

Why this matters

    The understanding of early endogenous mechanisms that regulate the autoimmune response in people with MS is limited.

    Understanding MS mechanisms can aid with clinical assessment, identification and timely diagnosis and treatment of MS.