Neurochemical levels and functional decline in patients with amyotrophic lateral sclerosis

Takeaway 

  • Changes in neurochemical levels in motor areas of the brain using proton magnetic resonance spectroscopy (1H-MRS) are associated with functional decline.

Why this matters

    This data demonstrates that 1H-MRS may be a useful outcomes measure for monitoring and disease progression in people with amyotrophic lateral sclerosis (ALS).