Neurodegeneration changes in isolated rapid eye movement behaviour disorder

Takeaway

  • People with isolated rapid eye movement behaviour disorder (iRBD) exhibit different patterns of brain hypometabolism that might reflect specific early pathophysiological events.

Why this matters

    iRBD is a risk factor for progression to Parkinson’s disease, dementia with Lewy Body and multiple system atrophy. These findings could help monitor and predict disease progression in people with iRBD.