Neurodevelopmental outcomes in preterm neonates exposed to perinatal inflammation


  • Exposure to early-onset perinatal inflammation is associated with decreased gross motor function and sociability scores at 30 months of corrected age (CA) in preterm neonates without severe brain injury.

Why this matters

  • No studies have assessed whether exposure to perinatal inflammation is associated with neurodevelopmental impairment in preterm children without severe neonatal brain injury.

  • Perinatal inflammatory conditions are potentially modifiable, and their management should be a focus of care in preterm infants in order to improve neurodevelopmental outcomes.