Neurofilament light chain levels are a potential blood biomarker of classic ataxia telangiectasia

Takeaway

  • Blood neurofilament light chain levels are elevated in children with classic ataxia telangiectasia.

Why this matters

  • This is the first study of blood neurofilament light chain levels in people with ataxia telangiectasia.

  • The elevated concentrations suggest that blood neurofilament light chain levels could be a promising biomarker of classic ataxia telangiectasia, although further studies are needed to determine if blood levels correlate with disease severity and progression.