Neurostimulation as treatment for epilepsy in people with tuberous sclerosis complex: a case series


  • In people with tuberous sclerosis complex-associated drug-resistant epilepsy (TSC-DRE) who underwent neurostimulation, the median number of disabling seizures after 1 year and after an average follow-up of 20 months was reduced relative to baseline.

Why this matters

    People with tuberous sclerosis complex (TSC) commonly experience refractory epilepsies and not all individuals can undergo resective or ablative surgery for treatment. Direct neurostimulation to seizure foci has proven effective in prior clinical trials and may serve as a new treatment option for people with TSC.