New antibodies to neurons, astrocytes, and oligodendrocytes identified in neurologic syndromes

Takeaway

  • Indirect immunofluorescence (IF) assay identifies previously unknown cerebrospinal fluid (CSF) antibodies to neurons, astrocytes, and oligodendrocytes in people with inflammatory neurologic syndromes.

Why this matters

    This study is the largest study in which CSF has been systematically analyzed for the most common neuronal and glia antibodies, with several new unknown antigen IgG to neuron, astrocyte and oligodendrocyte identified.