Non-invasive diffusion basis spectrum imaging reveals neuropathophysiology in multiple sclerosis

Takeaway

  • Diffusion basis spectrum imaging is a novel tool that reveals how damage to normal-appearing white matter in the corpus callosum affects neurologic disability in multiple sclerosis.

Why this matters

    Diffusion basis spectrum imaging permits non-invasive, quantitative assessment of the central nervous system in people with multiple sclerosis. It could be used as an outcome measure in clinical studies and to facilitate recruitment for future trials of potential neuroreparative multiple sclerosis therapies.