Novel angiopoietin-like 6 gene variants may be a genetic risk factor for intracranial aneurysms

Takeaway

  • The angiopoietin-like 6 gene variants could be a biomarker of familial intracranial aneurysms.

Why this matters

  • These novel findings highlight the importance of screening familial intracranial aneurysm cases for the angiopoietin-like 6 gene variant and also suggest that the angiopoietin-like 6 pathway could be a potential therapeutic target.