Observing early neuroaxonal injury in the acute phase of pediatric optic neuritis


  • The thinning of the ganglion cell inner plexiform layer (GCIPL) may be a marker of early neuroaxonal injury in children with optical neuritis (ON).

Why this matters

    There are many studies that use optical coherence tomography (OCT) to observe GCIPL and retinal nerve fiber layer (RNFL) thinning after an ON attack in adults. As fewer studies have used OCT in a pediatric cohort, this study sought to use the technique to evaluate changes in the retinal structure in a pediatric cohort with ON.