Occipital cortex hyperexcitability in people with visual snow syndrome with and without migraine

Takeaway

  • In people with visual snow syndrome (VS) with and without migraine, there was lower habituation in response to repetitive pattern reversal visual evoked potentials (rVEP) and reduced phosphene thresholds (PTs) compared with controls indicating occipital cortex hyperexcitability; more people with VS with migraine reported palinopsia (trailing), photophobia, and concentration difficulty compared to those without migraine.

Why this matters

  • VS is a distressing condition and neurophysiological assessments are a potential tool to diagnose VS and assess effectiveness of therapeutic agents.