Onset of sleep behavior disorder predicts progression and prognosis in multiple system atrophy

Takeaway

  • Rapid eye movement (REM) sleep behavior disorder is the most common initial symptom of disease in almost a third of people with multiple system atrophy.

Why this matters

    This is one of the largest follow-up studies to investigate REM sleep behavior disorder as type of disease onset in people with multiple system atrophy. The findings suggest that sleep disorders should be carefully assessed to enable early detection of REM sleep behavior disorder.