Outcomes of surgical resection of meningiomas in elderly patients

Takeaway

  • Evidence from a retrospective study suggests that surgical resection of large and giant skull base meningiomas is equally safe and effective in elderly patients as compared to younger patients.

Why this matters

  • Meningiomas, including skull base and non-skull base meningiomas, account for 25% of primary intracranial neoplasms in elderly patients.

  • Common management strategies for meningiomas include observation, radiosurgery and surgical resection, with choice of strategy depending on tumor size and patient age.

  • Surgical resection in the elderly population is controversial.

  • Skull base meningiomas in elderly patients are usually asymptomatic, slow growing and benign, meaning surgery may be unwarranted.

  • In addition, elderly patients may have poorer surgical and post-surgical outcomes than younger patients with meningiomas.

  • However, some studies suggest that the natural history of meningiomas tends towards malignancy and fast growth rate as elderly patients continue to age.