Evidence from a retrospective study suggests that surgical resection of large and giant skull base meningiomas is equally safe and effective in elderly patients as compared to younger patients.
Why this matters
Meningiomas, including skull base and non-skull base meningiomas, account for 25% of primary intracranial neoplasms in elderly patients.
Common management strategies for meningiomas include observation, radiosurgery and surgical resection, with choice of strategy depending on tumor size and patient age.
Skull base meningiomas in elderly patients are usually asymptomatic, slow growing and benign, meaning surgery may be unwarranted.
In addition, elderly patients may have poorer surgical and post-surgical outcomes than younger patients with meningiomas.
Surgical resection in the elderly population is controversial.
However, some studies suggest that the natural history of meningiomas tends towards malignancy and fast growth rate as elderly patients continue to age.