Oxidative stress biomarkers may aid in identifying ischemic penumbra in patients with acute ischemic stroke (AIS) seen within 9h of symptom onset.
Why this matters
The ischemic penumbra is a therapeutic target for reperfusion/recanalization therapy in AIS, and its timely identification may allow for improved patient selection.
Ischemic penumbra can be isolated through advanced neuroimaging techniques, but more practical, less expensive, and time-efficient methods are needed.
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