Oxidative stress biomarkers as a predictive tool for ischemic penumbra in acute stroke


  • Oxidative stress biomarkers may aid in identifying ischemic penumbra in patients with acute ischemic stroke (AIS) seen within 9h of symptom onset.

Why this matters

  • The ischemic penumbra is a therapeutic target for reperfusion/recanalization therapy in AIS, and its timely identification may allow for improved patient selection.

  • Ischemic penumbra can be isolated through advanced neuroimaging techniques, but more practical, less expensive, and time-efficient methods are needed.