Oxygen saturation and brain atrophy in individuals with sleep-disordered breathing


  • Lower levels of oxygen saturation during sleep was found to be related to atrophy of both cortical and subcortical brain areas.

  • Due to the lower oxygen saturation levels and resultant hypoxemia, behavioral phenotype and cognitive decline in patients with sleep-disordered breathing (SDB) may arise.

Why this matters

    This is the first study to show the relationship between markers of hypoxemia during sleep and brain anatomy in the general population, and could lead to the development of improved treatments and management strategies in those with SBD.