Pain sensitivity, pain catastrophizing and vascular alterations in Raynaud’s Phenomenon


  • People with primary and secondary Raynaud’s Phenomenon (PRP and SRP) had lower pressure pain thresholds and exhibited hypersensitivity compared to controls, but only those with SRP showed altered pain intensity and central sensitization; there was no association between basal hand temperatures and pain experiences.

Why this matters

  • Contrary to traditional beliefs, this study indicates that central pain experiences in RP do not correlate with level of vascular alterations, but that pain catastrophizing can influence pain especially if associated with another pathology.